Ampicillin

    Ampicillin :

    Antibiotic ID : UD0001

    Full Name : Ampicillin

    Synonyms : Omnipen, Ampicillin acid, Aminobenzylpenicillin, Polycillin, Principen, Amcill, Ampicilline, Penbritin, Pentrexyl

    Class : Beta Lactum

    Chemical Description :

    Molecular Formula : C16H19N3O4S

    Molecular Weight : 349.40476

    InChIKey : AVKUERGKIZMTKX-NJBDSQKTSA-N

    IUPAC Name : (2S,5R,6R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

    Structural Description :

    Canonical SMILES : CC1(C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=CC=C3)N)C(=O)O)C

    Isomeric SMILES : CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)[C@@H](C3=CC=CC=C3)N)C(=O)O)C

    2D Structure : 2D

    3D Structure : 3D

    SDF : SDF file

    Fuctional Description :

    Ampicillin Target : Semi-synthetic derivative of penicillin that functions as an orally active broad-spectrum antibiotic and inhibit the synthesis of cell wall. (MeSH)

    KEGG : D00204

    DRUG BANK : DB00415

    Pub Chem CID : 6249

    Antibiotics Resistance Reports :

    Upregulators :

    Enzyme : ß lactamase
    Genes : ampC (CITM, MOXM, DHAM, EBCM), ampD, ampE, ampG, ampH, blaTEM, blaSHV, blaOXA-1, blaOXA-7, blaCTX-M-3, blaPSE

    Downregulators : NA

    Note : NA* - Not Available

    Bibliography :