Penicillin

    Penicillin :

    Antibiotic ID : UD0034

    Full Name : Penicillin

    Synonyms : Benzylpenicillin, Pencillin G, Pfizerpen, Benzopenicillin, Abbocillin, Benzylpenicillin G, Dropcillin, Gelacillin, Liquacillin

    Class : Beta Lactum

    Chemical Description :

    Molecular Formula : C16H18N2O4S

    Molecular Weight : 334.39012

    InChIKey : JGSARLDLIJGVTE-MBNYWOFBSA-N

    IUPAC Name : (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(2-phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

    Structural Description :

    Canonical SMILES : CC1(C(N2C(S1)C(C2=O)NC(=O)CC3=CC=CC=C3)C(=O)O)C

    Isomeric SMILES : CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)CC3=CC=CC=C3)C(=O)O)C

    2D Structure : 2D

    3D Structure : 3D

    SDF : SDF file

    Fuctional Description :

    Penicillin Target : A penicillin derivative commonly used in the form of its sodium or potassium salts in the treatment of a variety of infections. It is effective against most gram-positive bacteria and against gram-negative cocci. It has also been used as an experimental convulsant because of its actions on GAMMA-AMINOBUTYRIC ACID mediated synaptic transmission (MeSH).

    KEGG : D02336

    DRUG BANK : DB01053

    Pub Chem CID : 5904

    Antibiotics Resistance Reports :

    Upregulators :

    Enzyme : Extended-spectrum β-lactamases(ESBLs), Plasmid-mediated AmpC β-lactamases, KPC carbapenemases, OXA-β-lactamases

    Downregulators : NA

    Note : NA* - Not Available

    Bibliography :