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Streptomycin
Streptomycin :
Antibiotic ID :
UD0039
Full Name :
Streptomycin
Synonyms :
Streptomycin sulphate, Kantrex, Streptomycin A, Streptomycin, Sulfate Salt, Streptomycin A sulfate, Streptomycin sulfate, Streptomycin (TN)
Class :
Beta Lactum
Chemical Description :
Molecular Formula :
C
21
H
39
N
7
O
12
Molecular Weight :
581.57406
InChIKey :
UCSJYZPVAKXKNQ-HZYVHMACSA-N
IUPAC Name :
2-[(1R,2R,3S,4R,5R,6S)-3-(diaminomethylideneamino)-4-[(2R,3R,4R,5S)-3-[(2S,3S,4S,5R,6S)-4,5-dihydroxy-6-(hydroxymethyl)-3-(methylamino)oxan-2-yl]oxy-4-formyl-4-hydroxy-5-methyloxolan-2-yl]oxy-2,5,6-trihydroxycyclohexyl]guanidine
Structural Description :
Canonical SMILES :
CC1C(C(C(O1)OC2C(C(C(C(C2O)O)N=C(N)N)O)N=C(N)N)OC3C(C(C(C(O3)CO)O)O)NC)(C=O)O
Isomeric SMILES :
C[C@H]1[C@@]([C@H]([C@@H](O1)O[C@@H]2[C@H]([C@@H]([C@H]([C@@H]([C@H]2O)O)N=C(N)N)O)N=C(N)N)O[C@H]3[C@H]([C@@H]([C@H]([C@@H](O3)CO)O)O)NC)(C=O)O
2D Structure :
2D
3D Structure :
3D
SDF :
SDF file
Fuctional Description :
Streptomycin Target :
An antibiotic produced by the soil actinomycete Streptomyces griseus. It acts by inhibiting the initiation and elongation processes during protein synthesis
(MeSH)
.
KEGG :
D08531
DRUG BANK :
DB01082
Pub Chem CID :
19649
Antibiotics Resistance Reports :
Upregulators :
External Factor :
Quartz attachment
Gene :
aadA1
Downregulators :
NA
Note :
NA* - Not Available
Bibliography :
Shiga Toxin-Producing Escherichia coli Isolated from Bovine Mastitic Milk: Serogroups, Virulence Factors, and Antibiotic Resistance Properties
, Momtaz H., Dehkordi F. S., Taktaz T., Rezvani A., and Yarali S.
, The Scientific World Journal
, 2012,
2012
:618709.
PMID:
23213293.
Association of antibiotic resistance in agricultural Escherichia coli isolates with attachment to quartz
, Liu P, Soupir ML, Zwonitzer M, Huss B, Jarboe LR.
, Applied and Environmental Microbiology
, 2011,
77
(19):6945-53.
PMID:
21821756