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Gene

emrR :

Gene ID : UG0051

Summary :

Full Name : mprA DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux [ Escherichia coli str. K-12 substr. MG1655 ]

Symbol : emrR

Also known as : ECK2678; emrR; JW2659

Gene description : DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux

Gene Position : 2810770..2811300

Gene strain : Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)

Transcription Factor : emrR

Lineage : Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Escherichia

Antibiotic Resistance Description :

Mutation : NA

Mechanism : Transcription Factor

Antibiotic :

Functional Description :

NCBI Gene ID : 945282

Patric : 32120760

GO : emrR

CDD : 188397

DEG : NA

Ecocyc : EG10603

KEGG : b2684

Uniprot : P0ACR9

Genomic context :

Gene – Protein : NP_417169.1

Sequence : Fasta

NA : Not available.

Bibliography :

Emr, an Escherichia coli locus for multidrug resistance, Lomovskaya O, Lewis K. , Proceedings of the National Academy of Sciences USA, 1992, 89(19):8938-42. PMID: 1409590.

EmrR is a negative regulator of the Escherichia coli multidrug resistance pump EmrAB., LomovsLomovskaya O, Lewis K, Matin A., Journal of Bacteriology, 1995, 177(9):2328-34. PMID: 7730261.

Overlaps and parallels in the regulation of intrinsic multiple-antibiotic resistance in Escherichia coli, Miller PF, Sulavik MC., Molecular Microbiology, 1996, 21(3):441-8. PMID: 8866468.

The EmrR protein represses the Escherichia coli emrRAB multidrug resistance operon by directly binding to its promoter region, Xiong A, Gottman A, Park C, Baetens M, Pandza S, Matin A., Antimicrobial Agents and Chemotherapy, 2000, 44(10):2905-7. PMID: 10991887.