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Gene

exbB :

Gene ID : UG0080

Summary :

Full Name : exbB membrane spanning protein in TonB-ExbB-ExbD complex [ Escherichia coli str. K-12 substr. MG1655 ]

Symbol : exbB

Also known as : ECK2999; JW2974

Gene description : membrane spanning protein in TonB-ExbB-ExbD complex

Gene Position : 3151250..3151984

Gene strain : Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)

Transcription Factor : exbB

Lineage : Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Escherichia

Antibiotic Resistance Description :

Mutation : NA

Mechanism : Transcription Factor

Antibiotic : Colicins

Functional Description :

NCBI Gene ID : 945420

Patric : 32121428

GO : exbB

CDD : 131844

DEG : NA

Ecocyc : EG10271

KEGG : b3006

Uniprot : P0ABU7

Genomic context :

Gene – Protein : NP_417479.1

Sequence : Fasta

NA : Not available.

Bibliography :

Linkage map of Escherichia coli K-12, edition 10: the traditional map, Berlyn MK., Microbiology and Molecular Biology Reviews, 1998, 62(3):814. PMID: 9729611.

Characterization of the exbBD operon of Escherichia coli and the role of ExbB and ExbD in TonB function and stability, Ahmer BM, Thomas MG, Larsen RA, Postle K., Journal of Bacteriology, 1995, 177(16):4742-7. PMID: 7642501.

The structurally related exbB and tolQ genes are interchangeable in conferring tonB-dependent colicin, bacteriophage, and albomycin sensitivity, Braun V., Journal of Bacteriology, 1989, 171(11):6387-90. PMID: 2553680.

Evolutionary relationship of uptake systems for biopolymers in Escherichia coli: cross-complementation between the TonB-ExbB-ExbD and the TolA-TolQ-TolR proteins, Braun V, Herrmann C., Molecular Microbiology, 1993, 8(2):261-8. PMID: 8316079.

Cloning and expression of the exbB gene of Escherichia coli K-12, Eick-Helmerich K, Hantke K, Braun V., Molecular Genetics and Genomics, 1987, 206(2):246-51. PMID: 3295484.

Import of biopolymers into Escherichia coli: nucleotide sequences of the exbB and exbD genes are homologous to those of the tolQ and tolR genes, respectively, Eick-Helmerich K, Braun V., Journal of Bacteriology, 1989, 171(9):5117-26. PMID: 2670903.

Involvement of ExbB and TonB in transport across the outer membrane of Escherichia coli: phenotypic complementation of exb mutants by overexpressed tonB and physical stabilization of TonB by ExbB, Bennett RL, Malamy MH., Journal of Bacteriology, 1989, 171(9):5127-34. PMID: 2670904.

Excretion of enterochelin by exbA and exbB mutants of Escherichia coli, Guterman SK, Dann L., Journal of Bacteriology, 1973, 114(3):1225-30. PMID: 4576403.

Topology of the ExbB protein in the cytoplasmic membrane of Escherichia coli, Kampfenkel K, Braun V., The Journal of Biological Chemistry, 1993, 268(8):6050-7. PMID: 8449962.

ExbB acts as a chaperone-like protein to stabilize TonB in the cytoplasm, Karlsson M, Hannavy K, Higgins CF., Molecular Microbiology, 1993, 8(2):389-96. PMID: 8100348.