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Gene
folA :
Gene ID :
UG0082
Summary :
Full Name :
folA dihydrofolate reductase [ Escherichia coli str. K-12 substr. MG1655 ]
Symbol :
folA
Also known as :
ECK0049; JW0047; tmrA
Gene description :
dihydrofolate reductase
Gene Position :
49823..50302
Gene strain :
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Transcription Factor :
folA
Lineage :
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Escherichia
Antibiotic Resistance Description :
Mutation :
NA
Mechanism :
Transcription Factor
Antibiotic :
Trimethoprim
Functional Description :
NCBI Gene ID :
944790
Patric :
32115195
GO :
folA
CDD :
182714
DEG :
NA
Ecocyc :
EG10326
KEGG :
b0048
Uniprot :
P0ABQ4
Genomic context :
Gene – Protein :
NP_414590.1
Sequence :
Fasta
NA : Not available.
Bibliography :
Linkage map of Escherichia coli K-12, edition 10: the traditional map
, Berlyn MK.
, Microbiology and Molecular Biology Reviews
, 1998,
62
(3):814.
PMID:
9729611.
Isolation and characterization of lambda transducing phages for the E. coli genes ksgA and pdxA
, Andrésson OS, Davies JE.
, Molecular Genetics and Genomics
, 1980,
179
(1):201-9.
PMID:
6450312.
The gene for Escherichia coli diadenosine tetraphosphatase is located immediately clockwise to folA and forms an operon with ksgA
, Blanchin-Roland S, Blanquet S, Schmitter JM, Fayat G.
, Molecular Genetics and Genomics
, 1986,
205
(3):515-22.
PMID:
3031429.
Cloning of dihydrofolate reductase gene of Escherichia coli K12
, Iwakura M, Shimura Y, Tsuda K.
, Journal of Bacteriology
, 1982,
91
(4):1205-12.
PMID:
7047510.
Genetic analysis of chromosomal resistance to trimethoprim derived from clinical isolates of Escherichia coli
, Pinn PA, Towner KJ, O'Grady FW.
, Journal of general microbiology
, 1983,
129
(1):85-92.
PMID:
6339680.
Cloning of the Escherichia coli K-12 dihydrofolate reductase gene following mu-mediated transposition
, Rood JI, Laird AJ, Williams JW.
, Gene
, 1980,
8
(3):255-65.
PMID:
6444603.