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Gene
gyrB :
Gene ID :
UG0025
Summary :
Full Name :
gyrB DNA gyrase, subunit B [ Escherichia coli str. K-12 substr. MG1655 ]
Symbol :
gyrB
Also known as :
acrB; Cou; ECK3691; himB; hisU; hopA; JW5625; nalC; parA; pcbA; pcpA
Gene description :
DNA gyrase, subunit B
Gene Position :
3877705..3880119
Gene strain :
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Transcription Factor :
ECK120000417
Lineage :
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Escherichia
Antibiotic Resistance Description :
Mutation :
Mutations in the genes encoding drug target DNA gyrase
Mechanism :
NA
Antibiotic :
Quinolones
Functional Description :
NCBI Gene ID :
948211
Patric :
NA
GO :
1384880517
CDD :
233254
DEG :
DEG10190253
Ecocyc :
EG10424
KEGG :
b3699
Uniprot :
P0AES6
Genomic context :
Gene – Protien :
YP_026241.1
Sequence :
Fasta
NA : Not available.
Bibliography :
Temporal interplay between efflux pumps and target mutations in development of antibiotic resistance in Escherichia coli
, Singh R, Swick MC, Ledesma KR, Yang Z, Hu M, Zechiedrich L, Tam VH.
, Antimicrobial Agents and Chemotherapy
, 2012,
56
(4) :1680-5.
PMID:
22232279.