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Gene
marA :
Gene ID :
UG0060
Summary :
Full Name :
marA DNA-binding transcriptional dual activator of multiple antibiotic resistance [ Escherichia coli str. K-12 substr. MG1655 ]
Symbol :
marA
Also known as :
cfxB; ECK1524; inaR; JW5249; nfxC; norB; soxQ
Gene description :
DNA-binding transcriptional dual activator of multiple antibiotic resistance
Gene Position :
1619574..1619957
Gene strain :
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Transcription Factor :
marA
Lineage :
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Escherichia
Antibiotic Resistance Description :
Mutation :
NA
Mechanism :
Transcription Factor
Antibiotic :
Functional Description :
NCBI Gene ID :
947613
Patric :
32118360
GO :
marA
CDD :
236920
DEG :
NA
Ecocyc :
EG11434
KEGG :
b1531
Uniprot :
P0ACH5
Genomic context :
Gene – Protein :
NP_416048.2
Sequence :
Fasta
NA : Not available.
Bibliography :
The mar regulon: multiple resistance to antibiotics and other toxic chemicals
, Alekshun MN, Levy SB
, Trends Microbiology
, 1999,
7
(10):410-3.
PMID:
10498949.
Organic solvent tolerance and antibiotic resistance increased by overexpression of marA in Escherichia coli
, Kobayashi M, Aono R
, Applied and Environmental Microbiology
, 1997,
63
(4):1428-33.
PMID:
9097440.
Genetic and functional analysis of the multiple antibiotic resistance (mar) locus in Escherichia coli
, Cohen SP, Hachler H, Levy SB
, Journal of Bacteriology
, 1993,
175
(5):1484-92.
PMID:
8383113.
Purification and regulatory properties of MarA protein, a transcriptional activator of Escherichia coli multiple antibiotic and superoxide resistance promoters
, Jair KW, Martin RG, Rosner JL, Fujita N, Ishihama A, Wolf RE
, Journal of Bacteriology
, 1995,
177
(24):7100-4.
PMID:
8522515.