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Gene

Gene ID : UG0061

Full Name : marR DNA-binding transcriptional repressor of multiple antibiotic resistance [ Escherichia coli str. K-12 substr. MG1655 ]

Symbol : marR

Also known as : cfxB; ECK1523; inaR; JW5248; soxQ

Gene description : DNA-binding transcriptional repressor of multiple antibiotic resistance

Gene Position : 1619120..1619554

Gene strain : Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)

Transcription Factor : marR

Lineage : Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Escherichia

Mutation : NA

Mechanism : Transcription Factor

Antibiotic :

NCBI Gene ID : 945825

Patric : 32118358

GO : marR

CDD : 224759

DEG : NA

Ecocyc : EG11435

KEGG : b1530

Uniprot : P27245

Gene – Protein : NP_416047.4

Sequence : Fasta

NA : Not available.

The crystal structure of MarR, a regulator of multiple antibiotic resistance, at 2.3 A resolution, Alekshun MN, Levy SB, Mealy TR, Seaton BA, Head JF, Nature Structural & Molecular Biology, 2001, 8(8):710-4. PMID: 11473263.

Regulation of chromosomally mediated multiple antibiotic resistance: the mar regulon, Alekshun MN, Levy SB, , Antimicrobial Agents Chemotherapy, 1997, 41(10):2067-75. PMID: 9333027.

In vivo increase in resistance to ciprofloxacin in Escherichia coli associated with deletion of the C-terminal part of MarR, Linde HJ, Notka F, Metz M, Kochanowski B, Heisig P, Lehn N., Antimicrobial Agents and Chemotherapy, 2000, 44(7):1865-8. PMID: 10858345.